Femtocells, which are low cost low power, stand alone cellular access points, are a potential solution to provide good indoor coverage with high data rate. However, the femtocell deployment may also increase the co-channel interference (CCI) by reducing the distance reuse of the spectrum. In this paper, we introduce methods to cancel out the interference among the femtocells while considering that macrocells operate orthogonally to the femtocells. The femtocells may also cooperate through joint detection of the received signal and improve the overall error performance at the expense of an increased computational complexity. In this paper, the performance-complexity tradeoff of cooperative detection is investigated for uplink transmissions. Numerical results show that the cooperative detection gain may reach 10 dB at a Bit-Error Rate (BER) of 10^-2 when compared to the case without cooperation.